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Galantamine increases hippocampal insulin-like growth factor 2 expression via α7 nicotinic acetylcholine receptors in mice

Conclusions  These findings suggest that galantamine increases hippocampal IGF2 levels via α7 nAChR activation in mice and imply that the
effect may contribute to its neuroprotection or neurogenesis.

Content Type Journal ArticleCategory Original InvestigationPages 1-9DOI 10.1007/s00213-012-2841-7Authors
Yuki Kita, Laboratory of Medicinal Pharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565-0871, JapanYukio Ago, Laboratory of Medicinal Pharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565-0871, JapanErika Takano, Laboratory of Medicinal Pharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565-0871, JapanAsak…

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Pharmacologic evidence to support clinical decision making for peripartum methadone treatment

Conclusions  Most women require increases in methadone dose across pregnancy. Given the shorter half-life and larger clearances during
pregnancy, many pregnant women may benefit from split methadone dosing. L/D increases quickly after delivery and doses should
be lowered rapidly after delivery.

Content Type Journal ArticleCategory Original InvestigationPages 1-11DOI 10.1007/s00213-012-2833-7Authors
D. L. Bogen, Department of Pediatrics, Division of General Academic Pediatrics, Children’s Hospital of Pittsburgh, University of Pittsburgh School of Medicine, 3414 Fifth Ave, CHOB 3rd floor, Pittsburgh, PA 15213, USAJ. M. Perel, Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USAJ. C. Helse…

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Pharmacologic evidence to support clinical decision making for peripartum methadone treatment

Conclusions  Most women require increases in methadone dose across pregnancy. Given the shorter half-life and larger clearances during
pregnancy, many pregnant women may benefit from split methadone dosing. L/D increases quickly after delivery and doses should
be lowered rapidly after delivery.

Content Type Journal ArticleCategory Original InvestigationPages 1-11DOI 10.1007/s00213-012-2833-7Authors
D. L. Bogen, Department of Pediatrics, Division of General Academic Pediatrics, Children’s Hospital of Pittsburgh, University of Pittsburgh School of Medicine, 3414 Fifth Ave, CHOB 3rd floor, Pittsburgh, PA 15213, USAJ. M. Perel, Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USAJ. C. Helse…

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Comparison of metabolic effects of ziprasidone versus olanzapine treatment in patients with first-episode schizophrenia

Conclusions  Compared with olanzapine, ziprasidone treatment was associated with less adverse effects on glucose and lipid metabolism in
patients with first-episode schizophrenia.

Content Type Journal ArticleCategory Original InvestigationPages 1-9DOI 10.1007/s00213-012-2850-6Authors
Jian-Jun Ou, Institute of Mental Health of the Second Xiangya Hospital, Central South University, 139 Middle Renmin Road, Changsha, 410011 Hunan, People’s Republic of ChinaYi Xu, The First Affiliated Hospital of Medical School of Zhejiang University, 79 Qingchun Road, Hangzhou, 310003 Zhejiang, People’s Republic of ChinaHong-Hui Chen, Wuhan Mental Health Center, 70 Qiaokou Youyi Road, Wuhan, 430022 Hubei, People’s Republic of ChinaXiaoduo Fan, UMass Memorial Medical Center, Universi…

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